Moreover, the vaccination coverage at each healthcare site was calculated through the ratio of the observed proportion of patients with a vaccination record and the expected rate of vaccination obtained from CDC reporting. The inclusion criteria to be eligible for the study included having either an International Classification of Diseases-10-Clinical Modification (ICD-10) COVID-19 diagnosis code or a SARS-CoV-2 antigen or PCR test along with a recorded health care visit between 120 and 300 days following index, having either completed vaccination status or not started vaccine regimen at index, being 18 years and older at index, and having at least two recorded health care visits in the year before the index. A COVID-19 index date was determined per the earliest indication of COVID-19 infection. All the analyses in the study were performed within the National COVID Cohort Collaborative (N3C) enclave that used electronic health records (EHRs) to obtain patient data. The study was a part of the National Institutes of Health (NIH) that developed the RECOVER initiative to treat, understand, and prevent PASC. Some studies indicate vaccines have a protective effect, while others report mixed or anti-protective effects.Ī new study posted to the pre-print server medRxiv* aimed to analyze the impact of pre-COVID-19 vaccination on long COVID diagnosis.

However, their impact on long COVID is not fully understood. Most studies have observed vaccines to be effective and safe at reducing the risk of severe COVID-19. Long COVID is the broad term used to define the ever-shifting symptoms of PASC. Several studies have indicated the occurrence of post-acute sequelae of SARS-CoV-2 infection (PASC) weeks after SARS-CoV-2 infection. Study: Long COVID Risk and Pre-COVID Vaccination: An EHR-Based Cohort Study from the RECOVER Program. The World Health Organization (WHO) has reported over 617 million confirmed cases and more than 6.5 million deaths associated with COVID-19 worldwide. The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to impact people's lives globally even after two years. By Suchandrima Bhowmik Reviewed by Aimee Molineux

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